1. Assuming you mean what domestiques to send, the key is to match the riders up with the race. A good hilly rider who is weak on the flats won't be useful in a race for the sprinters, but he will be on hilly classics. The key for stage races is to bring a mix of climbers to help with your leader there, and flat riders for the flat stages and lead-outs.
2. Assuming you are starting in 2010, Liquigas can handle everything except the cobbled classics (and even Quinzato can manage a top 10 or 15 occasionally there). Bennati can win sprints in any race. Nibali will be an outsider for the hilly classics, and Pellizoti and Basso will be outsiders for the GC contention. It'll be hard to win a GT or major classic, but podiums are definitely possible, and you really aren't restricted when it comes to what type of races you can compete in.
Another tactic could be to target the Giro or Vuelta hard with your stage race types, having several riders all peak for it...you could have a chance. TdF is probably out of reach though.
Pellizotti is always winning Giro with me. Nibali can win it aswell and also Giro. Basso i have no idea, never really followed him.
Tour is almost impossible, normally Contador will win there with 2min to A.Schleck and 5min to the 3rd. Top5 is definitly possible there.
I was 5th with Monfort on hard (78 mountain, 77 tt, Menchov crashed otherwise 6th)
I find that the Vuelta is usually the easiest of the GTs to win, as by then a lot of the favourites have over 60 days racing under their belts so their max fitness is reduced. So with the Giro being a climber's race this year, and the Vuelta having longer time trials I would use Pellizotti for the Giro and Nibali for the Vuelta. Basso could try for a top 5 in the Tour.
